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. 2022 Jul 11;19(8):1290–1299. doi: 10.7150/ijms.73645

Table 1.

Inclusion and Exclusion Criteria

Inclusion Criteria Exclusion Criteria
Male subjects (age 36 - 55 yrs, BMI: 22-29 kg/m2 History of taking medications for erectile dysfunction, oligospermia urinary and clinical history of endocrine disorders eg: pituitary tumors, hypo- and hyper-thyroidism.
Subjects with total AMS total between 27 and 43. Subjects diagnosed with sleep apnea and having history of psychiatric disorder.
Willingness to walk for 30 min/day (5 days/week) Subjects consuming alcohol or smoking and taken any medications that can interfere with muscle mass such as corticosteroids, testosterone replacement.
Healthy subjects with willing partners and good health Subjects under medications including anti-hypertensives, inhaled beta agonists, anti-hyperlipidemics, psychotropic and consume recreational drugs( cocaine) etc.
Ability to understand the risks and benefits of the protocol Subjects having history of Benign Prostate Hyperplasia (BPH), hypertension, diabetes, stroke, angina, life-threatening arrhythmia within the past 6 months.
Subjects should written ICF &available thought out the study Subjects using anorectic agents and endocannabinoid neuromodulators in last 2 weeks are prohibited.
Subjects agree to maintain the activity diary. Subjects with HIV positive or any other STDs and underwent major surgical procedures in last 6 months.
Subjects who agree not to start any therapies for sexual health or consuming energy boosting supplements or protein supplements or health drinks during the course of the study. Subject has illness as per the opinion of investigator.
Subjects willing to refrain from drinking coffee or caffeinated drinks or beverages during the study Subjects participated in any other clinical studies from last 90 days