Table 1.
Identification of differentially symmetrically dimethylated proteins.
| Accession | Gene | Description | MW [kDa] | Fold in CL1‐5 a | Fold in CL1‐0 b | Fold in H1650 b | Arginine Methylation site |
|---|---|---|---|---|---|---|---|
| P08670 | VIM | Vimentin | 53.6 | 5.4E+00 | 9.1E+05 | 1.7E+06 | Methyl [R64; R69; R196; R321; R345; R378] |
| Q92804 | TAF15 | TATA‐binding protein‐associated factor 2N | 61.8 | 3.0E+00 | 1.2E+07 | 6.0E+00 | Methyl [R562; R570] |
| Q7Z406 | MYH14 | Myosin‐14 | 227.7 | 2.7E+01 | 2.4E+00 | 1.6E+07 | Methyl [R189; R1912] |
| P14678 | SNRPB | Small nuclear ribonucleoprotein‐associated proteins B and B′ | 24.6 | 1.7E+01 | 2.6E+00 | 6.3E+06 | Methyl [R108] |
| P60709 | ACTB | Actin, cytoplasmic 1 | 41.7 | 6.2E+00 | 1.7E+01 | 2.4E+01 | Methyl [R62; R256; R372] |
| P35579 | MYH9 | Myosin‐9 | 226.4 | 1.6E+01 | 2.1E+00 | 6.9E+00 | Methyl [R104; R165; R341; R358; R775; R842; R867; R930; R1051; R1107; R1191; R1912] |
| P06733 | ENO1 | Alpha‐enolase | 47.1 | 2.6E+07 | 1.4E+07 | 2.6E+07 | |
| Q96P63 | SERPINB12 | Serpin B12 | 46.2 | 5.1E+06 | 8.8E+06 | 3.3E+06 | |
| P11182 | DBT | Lipoamide acyltransferase component of branched‐chain alpha‐keto acid dehydrogenase complex, mitochondrial | 53.5 | 9.5E+05 | 3.2E+07 | 8.0E+05 | |
| P38159 | RBMX | RNA‐binding motif protein, X chromosome | 42.3 | 2.4E+05 | 9.2E+06 | 3.3E+06 | |
| P08621 | SNRNP70 | U1 small nuclear ribonucleoprotein 70 kDa | 51.5 | 4.8E+05 | 1.5E+07 | 2.7E+00 | |
| P12956 | XRCC6 | X‐ray repair cross‐complementing protein 6 | 69.8 | 1.2E+07 | 2.5E+00 | 4.7E+06 | |
| P25311 | AZGP1 | Zinc‐alpha‐2‐glycoprotein | 34.2 | 1.6E+06 | 3.1E+00 | 3.2E+06 | |
| Q96DI7 | SNRNP40 | U5 small nuclear ribonucleoprotein 40 kDa protein | 39.3 | 5.3E+00 | 1.4E+06 | 7.0E+07 | |
| P81605 | DCD | Dermcidin | 11.3 | 2.8E+07 | 3.4E+00 | 2.3E+00 | |
| P04406 | GAPDH | Glyceraldehyde‐3‐phosphate dehydrogenase | 36.0 | 6.0E+06 | 5.5E+00 | 2.4E+00 | |
| P19338 | NCL | Nucleolin | 76.6 | 6.3E+00 | 8.5E+06 | 3.5E+00 | |
| O43172 | PRPF4 | U4/U6 small nuclear ribonucleoprotein Prp4 | 58.4 | 2.2E+00 | 8.2E+07 | 2.1E+00 | |
| Q00839 | HNRNPU | Heterogeneous nuclear ribonucleoprotein U | 90.5 | 5.4E+00 | 2.5E+00 | 2.2E+00 | |
| P09012 | SNRPA | U1 small nuclear ribonucleoprotein A | 31.3 | 3.6E+00 | 2.4E+00 | 6.1E+00 | |
| P07355 | ANXA2 | Annexin A2 | 38.6 | 2.7E+00 | 9.0E+00 | 6.2E+00 | |
| P61626 | LYZ | Lysozyme C | 16.5 | 2.6E+00 | 3.4E+00 | 2.2E+00 | |
| P42704 | LRPPRC | Leucine‐rich PPR motif‐containing protein, mitochondrial | 157.8 | 2.2E+00 | 5.0E+00 | 2.3E+00 | |
| P23246 | SFPQ | Splicing factor, proline‐ and glutamine‐rich | 76.1 | 2.1E+00 | 6.6E+01 | 2.1E+00 |
a
MTAP/Mock.
b
sgCTRL/sgMTAP.