Table 3. List of the screened DEPs after DFS administration.
| Accession | Protein name | Gene name | Fold change | p value |
|---|---|---|---|---|
| F1NT18 | Cytochrome P450 3A5 | CYP3A5 | +2.23 | 0.001035142 |
| Q90593 | Endoplasmic reticulum chaperone BiP | HSPA5 | +1.21 | 0.003515604 |
| A0A1D5P0U5 | Calreticulin | CALR | +1.20 | 0.018197009 |
| P00789 | Calpain-1 catalytic subunit | CAPN11 | −1.20 | 0.027542287 |
| F1P1M1 | UDP-glucuronosyltransferase | UGT1A1 | −1.21 | 0.011117317 |
| Q9I993 | Beta beta-carotene 15,15'-dioxygenase | BCO1 | −1.22 | 0.00311889 |
| Q5ZHY5 | STIP1 homology and U box-containing protein 1 | STUB1 | −1.24 | 0.047424199 |
| Q98UC3 | Ubiquitin fusion-degradation 1-like protein | Ufd1l | −1.24 | 0.001896706 |
| A0A1D5PCR2 | Protein transport protein Sec24B | SEC24B | −1.26 | 0.042854852 |
| E1BVB6 | Cytochrome P450 3A4 | CYP3A4 | −1.30 | 0.030269134 |
| F1NFM2 | Epimerase domain-containing protein | TDH | −1.33 | 0.02618183 |
| R4GII9 | Beta_elim_lyase domain-containing protein | LOC101747660 | −1.33 | 0.049773708 |
| F1NXN3 | Glycine amidinotransferase | GATM | −1.44 | 0.035237087 |
| A0A1D5PKQ8 | Cytochrome P450 2C45 | CYP2C45 | −2.76 | 0.001990673 |
DEP, differentially expressed protein; DFS, diclofenac sodium.
Plus and minus values of fold change represent the up- and down-regulated alteration trend of DEPs, respectively.