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. 2022 Jul 26;2022:3695848. doi: 10.1155/2022/3695848

Figure 2.

Figure 2

miR-369-3p is a crucial miRNA. (a) Top differentially expressed or crucial miRNAs are listed. (b) qPCR validation of differentially expressed key miRNAs (∗P < 0.05 vs. HuFCs-exosomes; ∗∗P < 0.01 vs. HuFCs-exosomes; t-test; n = 4). (c) The intersection of the miRNA-Seq results and the qPCR results. (d) Target predictions indicated more than one target for miR-369-3p (total context ++ score ≤ −0.26). (e) GO analysis showed that the target genes of miR-369-3p were most significant in the terms “cellular process,” “molecular interaction,” and “cellular anatomical entities.” (f) KEGG analysis showed that the genes were involved in the gonadotropin-releasing hormone receptor pathway and the Huntington disease pathway.