Table 1.
Diversity of peptide signalling molecules. Gram-positive species demonstrate a wide variety of peptide signalling molecules.
| species | signal | sequence/structure |
|---|---|---|
| Enterococcus faecalis | GBAP | QN(SPNIFGQWM)a |
| Staphylococcus aureus | AIP-I | YST(CDFIM)a |
| Streptococcus pneumoniae | CSP1 | EMRLSKFFRDFILQRKK |
| Streptococcus pneumoniae | CSP2 | EMRISRIILDFLFLRKK |
| Streptococcus pyogenes | SHP2 | IMDILIIVGG |
| MDILIIVGG | ||
| DILIIVGG—most active | ||
| Streptococcus mutans | XIP | GLDWWSL |
| Streptococcus gallolyticus | GSP | DFLIVGPFDWLKKNHKPTK |
aAmino acids in parenthesis represent macrocyclic portions of the peptide.