Table 4.

Multilevel Models: Concurrent Associations of RDoC Constructs with HBQ and DISC at Age 7

Outcome HBQ	Predictors	Estimate	s.e.	p-value	FDR p-value	Outcome DISC	Predictors	Estimate	s.e.	p-value	FDR p-value
Depression	Reward Responsiveness	−0.001	0.012	0.9161	0.9457	Depression	Reward Responsiveness	0.114	0.064	0.0766	0.1572
	Frustrative Nonreward	0.020	0.013	0.1147	0.1913		Frustrative Nonreward	0.153	0.065	0.0184	0.0595
	Loss	0.034	0.014	0.0186	0.0595		Loss	0.251	0.072	0.0005	0.0036**
	Fear	0.024	0.010	0.0197	0.0600		Fear	0.089	0.056	0.1104	0.1910
Overanxiousness	Reward Responsiveness	−0.001	0.016	0.9630	0.9630	Generalized Anxiety	Reward Responsiveness	0.012	0.066	0.8560	0.8981
	Frustrative Nonreward	0.014	0.016	0.3857	0.5610		Frustrative Nonreward	0.075	0.068	0.2721	0.4050
	Loss	0.049	0.019	0.0095	0.0380*		Loss	0.149	0.075	0.0483	0.1104
	Fear	0.030	0.013	0.0231	0.0672		Fear	0.081	0.056	0.1502	0.2403
Separation Anxiety	Reward Responsiveness	−0.011	0.017	0.5074	0.6622	Separation Anxiety	Reward Responsiveness	−0.131	0.070	0.0618	0.1318
	Frustrative Nonreward	0.010	0.018	0.5618	0.6622		Frustrative Nonreward	0.113	0.072	0.1166	0.1913
	Loss	0.013	0.021	0.5231	0.6622		Loss	0.105	0.079	0.1842	0.2807
	Fear	0.031	0.014	0.0309	0.0824		Fear	0.050	0.060	0.4010	0.5703
Inhibition	Reward Responsiveness	−0.115	0.022	<.0001	<.0001***	Social Anxiety	Reward Responsiveness	−0.261	0.110	0.0174	0.0595
	Frustrative Nonreward	−0.109	0.023	<.0001	<.0001***		Frustrative Nonreward	−0.231	0.120	0.0541	0.1194
	Loss	0.012	0.026	0.6363	0.7144		Loss	0.328	0.124	0.0084	0.0358*
	Fear	0.063	0.018	0.0007	0.0045**		Fear	0.294	0.096	0.0022	0.0128*
Impulsivity	Reward Responsiveness	0.088	0.022	<.0001	<.0001***	Specific Phobia	Reward Responsiveness	0.027	0.066	0.6797	0.7373
	Frustrative Nonreward	0.108	0.023	<.0001	<.0001***		Frustrative Nonreward	0.040	0.068	0.5578	0.6622
	Loss	0.060	0.027	0.0257	0.0715		Loss	0.151	0.075	0.0445	0.1055
	Fear	0.015	0.019	0.4179	0.5814		Fear	0.094	0.056	0.0951	0.1739
Opposition	Reward Responsiveness	−0.009	0.021	0.6614	0.7298	ADHD	Reward Responsiveness	0.227	0.056	<.0001	<.0001***
	Frustrative Nonreward	0.076	0.022	0.0005	0.0036**		Frustrative Nonreward	0.277	0.055	<.0001	<.0001***
	Loss	0.053	0.025	0.0357	0.0914		Loss	0.190	0.062	0.0024	0.0128*
	Fear	0.013	0.018	0.4669	0.6225		Fear	0.029	0.049	0.5557	0.6622
Overt Aggression	Reward Responsiveness	0.025	0.019	0.1783	0.2783	Conduct Disorder	Reward Responsiveness	0.056	0.088	0.5281	0.6622
	Frustrative Nonreward	0.033	0.020	0.0921	0.1734		Frustrative Nonreward	0.307	0.086	0.0004	0.0036**
	Loss	0.054	0.023	0.0176	0.0595		Loss	0.172	0.098	0.0786	0.1572
	Fear	−0.005	0.016	0.7736	0.8252		Fear	0.058	0.077	0.4488	0.6111
Relational Aggression	Reward Responsiveness	0.027	0.017	0.1059	0.1883	Oppositional Defiant	Reward Responsiveness	0.016	0.033	0.6352	0.7144
	Frustrative Nonreward	0.030	0.017	0.0818	0.1586		Frustrative Nonreward	0.097	0.034	0.0043	0.0212*
	Loss	0.054	0.020	0.0069	0.0315*		Loss	0.078	0.039	0.0430	0.1055
	Fear	0.001	0.014	0.9564	0.9630		Fear	0.016	0.028	0.5691	0.6622

Note. HBQ: MacArthur Health and Behavior Questionnaire; average of mother and father report. DISC: Diagnostic Interview Schedule for Children-IV symptom counts; primary caregiver report. FDR: False Discovery Rate.

^*p < .05,

^**p <.01,

^***p < .001.

Significance reported only for FDR p-values.