Table 3. PPI network analysis results for SLC2A1-related differential genes.
| MCODE | ID | Description | Log10 (P) |
|---|---|---|---|
| MCODE_1 | R-HSA-2500257 | Resolution of Sister Chromatid Cohesion | −44 |
| MCODE_1 | R-HSA-68882 | Mitotic Anaphase | −41.9 |
| MCODE_1 | R-HSA-2555396 | Mitotic Metaphase and Anaphase | −41.9 |
| MCODE_2 | R-HSA-163125 | Post-translational modification: synthesis of glycosylphosphatidylinositol (GPI)-anchored proteins | −11.3 |
| MCODE_2 | R-HSA-6798695 | Neutrophil degranulation | −7 |
| MCODE_2 | GO:0031638 | zymogen activation | −5.4 |
| MCODE_3 | R-HSA-983189 | Kinesins | −6.8 |
| MCODE_3 | R-HSA-6811434 | Coat protein complex I (COPI)-dependent Golgi-to-endoplasmic reticulum (ER) retrograde traffic | −6.1 |
| MCODE_3 | R-HSA-2132295 | Major histocompatibility complex (MHC) class II antigen presentation | −5.8 |
| MCODE_4 | R-HSA-6809371 | Formation of the cornified envelope | −11.7 |
| MCODE_4 | R-HSA-6805567 | Keratinization | −10.6 |
| MCODE_4 | GO:0002009 | morphogenesis of an epithelium | −4.2 |
| MCODE_5 | R-HSA-5688890 | Defective CSF2RA causes SMDP4 | −18.8 |
| MCODE_5 | R-HSA-5688849 | Defective CSF2RB causes SMDP5 | −18.8 |
| MCODE_5 | R-HSA-5687613 | Diseases associated with surfactant metabolism | −18.1 |
| MCODE_6 | R-HSA-983189 | Kinesins | −10.8 |
| MCODE_6 | R-HSA-6811434 | COPI-dependent Golgi-to-ER retrograde traffic | −9.8 |
| MCODE_6 | R-HSA-8856688 | Golgi-to-ER retrograde transport | −9.3 |
| MCODE_7 | R-HSA-1650814 | Collagen biosynthesis and modifying enzymes | −10.5 |
| MCODE_7 | R-HSA-1474290 | Collagen formation | −10 |
| MCODE_7 | R-HSA-1474244 | Extracellular matrix organization | −7.9 |
| MCODE_8 | R-HSA-418594 | G alpha (i) signaling events | −7.8 |
| MCODE_8 | R-HSA-373076 | Class A/1 (Rhodopsin-like receptors) | −7.7 |
| MCODE_8 | R-HSA-500792 | g-protein coupled receptor (GPCR) ligand binding | −7.1 |
| MCODE_9 | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity | −7.4 |
| MCODE_9 | GO:1904029 | regulation of cyclin-dependent protein kinase activity | −7.3 |
| MCODE_9 | WP179 | Cell cycle | −7.1 |
| MCODE_10 | R-HSA-8957275 | Post-translational protein phosphorylation | −7.3 |
| MCODE_10 | R-HSA-381426 | Regulation of insulin-like growth factor (IGF) transport and uptake by insulin-like growth factor binding proteins (IGFBPs) | −7.1 |
| MCODE_11 | M65 | PID FRA PATHWAY | −8.7 |
| MCODE_11 | M167 | PID AP1 PATHWAY | −7.8 |
PPI, protein-protein interaction.