Table 3.
Variable | Ciprofol group (n = 60) |
Propofol group (n = 60) |
P-value |
---|---|---|---|
Intubation response, n(%) | |||
swallowing, | 0 | 3(5%) | |
cough | 0 | 1(1.67%) | |
body moving | 0 | 2(3.33%) | |
tears | 0 | 1(1.67%) | |
hypertension | 4(6.67%) | 2(3.33%) | |
hypotension | 5(8.33%) | 16(26.67%) | |
bradycardia | 2(3.33%) | 1(1.67%) | |
tachycardia | 1(1.67%) | 3(5%) | |
total | 12(20%) | 29(48.33%) | 0.0019 |
Injection-site pain, n(%) | 10(16.7%) | 35(58.3%) | < 0.001 |
Hypertension, hypotension, bradycardia and tachycardia were defined as occurred within 10 min after administration of the study drug were recorded; hypertension: an increase of 20% than baseline value; hypotension: an decrease of 20% than baseline; bradycardia: heart rates less than 55 beats/min; tachycardia: heart rates more than 100 beats/min; Injection-site pain: with a withdrawal response or a numeric rating scale value ≥ 3