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. 2022 Aug 3;28:88. doi: 10.1186/s10020-022-00494-5

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 10 — ERS inhibits ROS levels in kidney tissue of mice and HK-2 cell. A The expressions of GPR78 and SOD1 in the kidney of model mice were detected by immunofluorescence. B, C The level of ROS in HK-2 cell model was detected by fluorescence microscope and flow cytometry. D Western blot was used to detect the expression of ERS and ROS related proteins protein in HK-2 cell model. (*compared with normal control group, P < 0.05.*^(Red)Compared with control group, P < 0.01. ^#Compared with oxalate group, P < 0.05. ^#(Red)Compared with oxalate group, P < 0.01)