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. 2022 Aug 3;28:88. doi: 10.1186/s10020-022-00494-5

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — Oxalate activates the NF-κB pathway by stimulating ERS in HK-2 cells. A Ultrastructure observation of each group under transmission electron microscope. B, C Western blot was used to detect the expression of ERS-related proteins in each group. D, E Western blot was used to detect the expression of NF-κB pathway proteins in each group. (*compared with normal Control group, P < 0.05.*^(Red)Compared with Control group, P < 0.01. ^#Compared with oxalate group, P < 0.05. ^#(Red)Compared with oxalate group, P < 0.01)