TABLE 2.
Right heart catheterization responses
| All Subjects (n=20) | Training-Testing Set Subjects (n=15) | Validation Set Subjects (n=5) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| BL | VI | p-Value | BL | VI | p-Value | BL | VI | p-Value | |
| PAMP, mmHg | 34 (32–37) | 26 (24–28) | <0.001 | 35 (31–38) | 26 (24–28) | <0.001 | 33 (32–34) | 26 (24–28) | 0.062 |
| PCWP, mmHg | 22 (18–25) | 13 (12–17)* | <0.001 | 21 (18–26) | 14 (10–18)* | <0.001 | 22 (21–24) | 13 (13–16) | 0.062 |
| HR_PA, BPM | 82 (69–94) | 85 (69–93)* | 0.736 | 82 (70–94) | 89 (70–94) | 0.68 | 70 (67–88) | 72 (67–92) | 1 |
| HR_PCW, BPM | 80 (69–90) | 79 (69–90) | 0.42 | 80 (67–90) | 78 (69–89)* | 0.328 | 87 (72–89) | 88 (75–90) | 0.5625 |
| RAMP, mmHg | 9 (7–13) | 7 (5–11)* | 0.002 | 9 (6–14) | 7 (5–11)* | 0.008 | 10 (9–13) | 7 (6–7)* | 0.5 |
| SV, mL/beat | 47 (40–65)* | 65 (47–75)* | 0.059 | 46 (39–61)* | 60 (48–80)* | 0.03 | 59 (43–68) | 66 (46–68) | 1 |
| Fick CO, L/min | 3.8 (3.4–4.6)* | 4.6 (4–5.3)* | 0.01 | 3.8 (3.3–4.3)* | 4.5 (4–5.5)* | 0.045 | 4.1 (3.5–4.7) | 4.6 (4–4.9) | 0.25 |
| Thermodilution CO, L/min | 3.7 (3.3–4.4)* | 4.6 (3.7–5.6)* | 0.002 | 3.5 (3.3–4.4) | 4.6 (3.7–5.8)* | 0.007 | 3.9 (3.5–4.2)* | 4.1 (3.7–4.9) | 0.25 |
| CI, L/min/m2 | 1.8 (1.7–2) | 2.1 (1.9–2.7)* | <0.001 | 1.8 (1.7–2) | 2.2 (1.9–2.7)* | 0.002 | 1.9 (1.7–2) | 2.1 (2.1–2.2) | 0.188 |
*
Missing values for one or more subjects.
Values shown are median (25th-75th percentiles) unless otherwise indicated. Statistical significance between BL and VI periods in values, where applicable, was evaluated using a Wilcoxon signed rank test. BL, Baseline Values; VI, Vasodilator Infused values, PAMP, Pulmonary Artery Mean Pressure, PCWP, Pulmonary Capillary Wedge Pressure, RAMP, Right Atrial Mean Pressure, SV, Stroke Volume, CO, Cardiac Output, CI, Cardiac Index.