NCT05022472 (2VIDA!).

Study name	Project 2VIDA! COVID‐19 Vaccine Intervention Delivery for Adults in southern California (2VIDA!)
Starting date	26 August 2021
Contact information	Argentina E Servin, MD,MPH; 6195767211; arservin@ucsd.edu
Methods	Study design: randomised controlled trial Type of publication: trial registration Setting: Latino and African American (AA) communities in Southern California, NR Country: USA Language: English and Spanish
Intervention	Multidimensional community intervention Behavioral: COVID‐19 Individual Awareness and Education. Behavioral: COVID‐19 Community Outreach & Health Promotion. Behavioral: COVID‐19 Individual Health Education & Linkages to Medical and Supportive Services. Biological: Pop‐up community vaccination sites No intervention: standard care (Standard for vaccine delivery)
Population	Population: general population Inclusion criteria:  age 18 years or older identify as Latinx and/or AA biologically male or female be a resident of one of the six communities selected for this study (National City, Lincoln Park, Logan Heights, Valencia Park, Chula Vista or San Ysidro) literate in English or Spanish no known history of severe allergic reactions to any components of the vaccine no history of immune disease not pregnant no plans to move from the area in the following 30 days able to provide voluntary informed consent able to provide complete contact information for themselves and two additional contact individuals (for follow‐up 2nd vaccine shot) Exclusion criteria:  under 18 years old pregnant women adults unable to consent
Outcomes	Primary outcomes COVID‐19 vaccine acceptance Vaccine hesitancy Secondary outcomes Change in health literacy  Change in COVID‐19 risk perception Change in preparedness and perceived self‐efficacy Change in prevention (own behaviours)  Testing and tracing Access to health care and utilisation Health history Other outcomes Affect  Use of sources of information Policies and interventions (perceptions)  Trust in sources of information Frequency of information Perceptions of government responses to COVID‐19 pandemic Trust in institutions (perceptions)  Conspiracies (perceptions) Resilience (perceptions)
Estimated completion date and number of participants	31 January 2026, 1000 participants
Notes	COI: NR Funding: Argentina Servin, MD, MPH