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. 2022 Jul 13;33(13-14):695–707. doi: 10.1089/hum.2021.272

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© Tiffany S. Nelson et al., 2022. Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons Attribution Noncommercial License [CC-BY-NC] (http://creativecommons.org/licenses/by-nc/4.0/) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are cited.

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Figure 5. — Rate of lactate secretion in excised P23H^+/− retinas. Retinas were extracted 60 days postinjection and secreted lactate concentrations determined as described. (A) Examples of lactate secretion curves from retinas obtained from P23H^+/− eyes treated with AAV-ArrGG (green), AAV-ArrWT (red), or buffer (gray). (B) Average lactate secretion rates in retinal explants from mice treated with ArrGG (green; n = 4), with ArrWT (red; n = 4), or buffer only (gray; n = 8); bars show mean ± SEM, asterisk indicates statistically significant difference in one-way ANOVA with Tukey's post hoc comparison (ρ < 0.05). Color images are available online.