Table 2.
Gross Morphology and Biochemical Data of Neocartilage Constructs Treated with Two or More Ion Modulators
| Diameter (mm) | Thickness (mm) | Wet weight (mg) | Hydration (%) | DNA/const. (μg) | Collagen (%WW) | GAG (%WW) | PYR (ng PYR/mg WW) | |
|---|---|---|---|---|---|---|---|---|
| Control+ | 5.28 ± 0.02 | 0.51 ± 0.02 | 14.5 ± 0.4 | 66.5 ± 7.1 | 25.7 ± 4.3 | 5.01 ± 0.13 | 12.19 ± 0.97 | 150.09 ± 76.51 |
| 4α+Ou | 5.32 ± 0.07 | 0.46 ± 0.05 | 13.3 ± 0.6* | 71.5 ± 2.5 | 21.1 ± 1.5 | 4.75 ± 0.57 | 10.27 ± 0.95 | 237.17 ± 24.54* |
| 4α+ Io | 5.36 ± 0.07 | 0.51 ± 0.03 | 14.4 ± 1.2 | 70.5 ± 4.0 | 19.2 ± 5.9 | 4.49 ± 0.68 | 11.76 ± 1.74 | 157.73 ± 60.74 |
| Ou+ Io | 5.29 ± 0.10 | 0.51 ± 0.03 | 13.7 ± 0.4 | 74.9 ± 8.2 | 22.2 ± 7.5 | 4.33 ± 1.39 | 8.00 ± 3.28* | 174.63 ± 64.84 |
| 4α+Ou+ Io | 5.35 ± 0.08 | 0.49 ± 0.04 | 13.5 ± 0.6* | 71.9 ± 8.4 | 27.3 ± 4.5 | 5.17 ± 1.31 | 9.92 ± 2.16 | 141.24 ± 33.71 |
Data are presented as mean ± standard deviation. The asterisks denote significant differences compared with the control+ group based of Dunnett's post hoc test. *Denotes p < 0.05.