FIGURE 5.

Pharmacophore features of flavonoids required for the anti‐SARS‐CoV‐2 activity. (a) Common pharmacophore generation sites with distance in Å with two acceptors [pink sphere with two arrows], two aromatic rings [dark yellow circle], and one donor [blue sphere with arrow]. (b) Alignment of all active flavonoids including silibinin, myricetin and eriodictyol to the pharmacophore. (c) The good alignment of the active silibinin to the pharmacophore. (d) The bad alignment of inactive daidzein to the pharmacophore