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. 2022 Jun 3;94(9):4533–4538. doi: 10.1002/jmv.27882

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© 2022 Wiley Periodicals LLC.

This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.

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Binding antibody titer induced by the third‐dose booster vaccination with each receptor‐binding domain (RBD) variant against the RBD proteins of wild‐type severe acute respiratory syndrome coronavirus 2 and its variants. Binding antibody titer of the sera after the third‐dose booster vaccination with wild type, Alpha, Beta, Gamma, Delta, Kappa, or Omicron against the RBD of (A) wild type, (B) Alpha, (C) Beta, (D) Gamma, (E) Delta, or (F) Omicron. The ratio of antibody titer against each variant to antibody titer against wild‐type strains is shown, black bars indicate mean values. Statistical analysis was performed using the paired t‐test.