Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jun 16;94(10):4780–4791. doi: 10.1002/jmv.27927

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 Wiley Periodicals LLC.

This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.

PMC Copyright notice

Docking between (A) wild‐type (WT)‐RBD (B) Omicron BA.1‐RBD, and (C) Omicron BA.1.1‐RBD (D) Omicron BA.2‐RBD (E) Omicron BA.3‐RBD with hACE2. Based on docking energy it shows Omicron BA.2 and BA.3‐RBD have a high binding affinity with hACE2 compared to Omicron variant BA.1, B.1.1, and WT. Docking scores are shown in MM/GBSA free energy decomposition analysis for binding free energy calculations at the top of each variant. hACE2, human angiotensin I‐converting enzyme 2; RBD, receptor‐binding domain.