TABLE 1.
Characteristics of veterans hospitalized for COVID‐19, stratified by remdesivir treatment
| N = 4125, mean (SD), N (%) | No remdesivir, N = 2428 | Remdesivir, N = 1697 | p value |
|---|---|---|---|
| Age, years | 70.4 (12.2) | 71.3 (10.2) | 0.008 |
| Sex, female | 146 (6.0) | 95 (5.6) | 0.62 |
| Population a | |||
| White | 1537 (63.3) | 1192 (70.2) | <0.001 |
| Black | 891 (36.7) | 505 (29.8) | |
| BMI, kg/m2 | 29.7 (6.8) | 31.0 (7.1) | <0.001 |
| Charlson comorbidity index | 4.8 (3.8) | 5.1 (3.4) | 0.005 |
| Glomerular filtration rate, ml/min | 67.2 (24.0) | 67.8 (20.4) | 0.43 |
| Serum creatine, mg/dl | 1.3 (0.6) | 1.2 (0.4) | <0.001 |
| Diabetes | 1286 (53.0) | 938 (55.3) | 0.15 |
| Hypertension | 2022 (83.3) | 1397 (82.3) | 0.45 |
|
Length of stay, days Median (IQR) |
4 (2, 9) | 7 (5, 14) | <0.001 |
|
ALT baseline, U/L Median (IQR) |
24 (16, 36) | 27 (19, 41) | <0.001 |
|
AST baseline, U/L Median (IQR) |
27 (19, 40) | 36 (25, 52) | <0.001 |
|
Total bilirubin baseline, mg/dl Median (IQR) |
0.60 (0.40, 0.80) | 0.64 (0.50, 0.90) | <0.001 |
| Alkaline phosphatase baseline, U/L Median (IQR) | 77 (62, 98) | 71 (57, 91) | <0.001 |
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; COVID‐19, coronavirus disease 2019; HARE, harmonized ancestry, race, and ethnicity; IQR, interquartile range.
a
Population determined by HARE ancestry.