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. 2022 May 11:e14219. Online ahead of print. doi: 10.1111/jfbc.14219

FIGURE 3.

FIGURE 3

Type of interaction of crocin with the key interacting amino acid residues of (a) Mpro and (b) replication complex of SARS‐CoV‐2. The green‐colored and blue‐colored bars refer to the presence of H‐bonding and the presence of water bridges, respectively. Purple‐colored and dark pink‐colored bars demonstrate the presence of hydrophobic interactions and the presence of ionic interactions between the macromolecular residues and the complexed ligand, respectively