Table 1. Design of experiment of drug release system .
| Experiment code | Feeding ratio of sheath to core | Polymer ratio in sheath (PCL:CS, v:v) | Nanoparticle % | Drug % | Magnetic field frequency, kHz |
| C1 | 1.25 | 2:1 | 1 | 3 | 0 |
| C2 | 1.25 | 2:1 | 3 | 1 | 400 |
| C3 | 1.25 | 2:1 | 7 | 5 | 300 |
| C4 | 1.25 | 1:1 | 1 | 5 | 400 |
| C5 | 1.25 | 1:1 | 3 | 3 | 300 |
| C6 | 1.25 | 1:1 | 7 | 1 | 0 |
| C7 | 1.25 | 1:2 | 1 | 1 | 300 |
| C8 | 1.25 | 1:2 | 3 | 5 | 0 |
| C9 | 1.25 | 1:2 | 7 | 3 | 400 |
| C10 | 2 | 2:1 | 1 | 1 | 400 |
| C11 | 2 | 2:1 | 3 | 5 | 300 |
| C12 | 2 | 2:1 | 7 | 3 | 0 |
| C13 | 2 | 1:1 | 1 | 5 | 0 |
| C14 | 2 | 1:1 | 3 | 3 | 400 |
| C15 | 2 | 1:1 | 7 | 1 | 300 |
| C16 | 2 | 1:2 | 1 | 3 | 300 |
| C17 | 2 | 1:2 | 3 | 1 | 0 |
| C18 | 2 | 1:2 | 7 | 5 | 400 |