Table 1.
Demographic and Clinical Characteristics of Human Patients from Whom Originate the BALF Cells Analyzed by Bulk and Single-Cell RNA Sequencing
| HD1 | HD2 | HD3 | HD4 | HD5 | HD6 | HD7 | HD8 | HD9 | |
|---|---|---|---|---|---|---|---|---|---|
| Status | Healthy nonsmoker |
Smoker without COPD |
Smoker with COPD |
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| Age | 60 | 56 | 56 | 56 | 56 | 40 | 63 | 60 | 65 |
| BMI | 28.95 | 26.2 | 25.7 | 20.83 | 24.1 | 30.1 | 20.34 | 23.5 | 25.95 |
| Males/Female | F | M | M | F | M | M | M | M | M |
| Ethnicity | Caucasian |
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| Smoker status | Nonsmoker |
Current smoker |
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| Pack-years | 0 | 0 | 0 | 13 | 41 | 24 | 40 | 35 | 55 |
| FEV, % predicted | 123 | 98 | 108 | 106 | 94 | 96 | 45 | 63 | 81 |
| FEV/FVC, % | 89.9 | 74 | 78 | 88.7 | 80 | 84 | 47 | 59 | 64 |
| Leucocytes counts, 106 c/L | 53.1 | 46.22 | 41.7 | 91.4 | 564 | 46.2 | 61.7 | 100 | 206 |
| GOLD COPD stage | NA | NA | NA | NA | NA | NA | III | II | II |
| Corticoids, yes/no | NA | NA | NA | NA | NA | NA | No | Yes | Yes |
Definition of abbreviations: BMI = body mass index; COPD = chronic obstructive pulmonary disease; FEV = forced expiratory volume; FVC = forced vital capacity; GOLD = Global Initiative for COPD; HD = human donor; NA = not applicable.