Table 1. GPC3 expression according to baseline characteristics.
| Characteristics | All patients (n = 59)
(n, %) |
GPC3 expression |
P-value
(Fisher’s exact test) |
|
|---|---|---|---|---|
| Negative (n = 20)
(n, %) |
Positive (n = 39)
(n, %) |
|||
| Age (*) | 0.780 | |||
| > median (80.5 y) | 29 (50.0) | 10 (52.6) | 19 (48.7) | |
| < median (80.5 y) | 29 (50.0) | 9 (47.4) | 20 (51.3) | |
| Sex (*) | 0.048 | |||
| Female | 35 (60.3) | 8 (42.1) | 27 (69.2) | |
| Male | 23 (39.7) | 11 (57.9) | 12 (30.8) | |
| AJCC stage (at diagnosis) (*) | 0.162 | |||
| Stage 1 | 20 (34.5) | 8 (42.1) | 12 (30.8) | |
| Stage 2 | 19 (32.8) | 3 (15.8) | 16 (41.0) | |
| Stage 3 | 18 (31.0) | 8 (42.1) | 10 (25.6) | |
| Stage 4 | 1 (1.7) | 0 (0.0) | 1 (2.6) | |
| Immunosuppression (*) | 0.975 | |||
| No | 52 (89.7) | 17 (89.5) | 35 (89.7) | |
| Yes | 6 (10.3) | 2 (10.5) | 4 (10.3) | |
| Location of primary (*) | 0.897 | |||
| head and neck | 19 (32.8) | 5 (26.3) | 12 (30.8) | |
| limb | 28 (48.3) | 10 (52.6) | 16 (41.0) | |
| trunk | 5 (8.6) | 2 (10.5) | 10 (25.6) | |
| occult primary | 6 (10.3) | 2 (10.5) | 1 (2.6) | |
| Type of sample | 0.594 | |||
| Primary | 41 (69.5) | 13 (65.0) | 28 (71.8) | |
| Metastasis | 18 (30.5) | 7 (35.0) | 11 (28.2) | |
| MCPyV status (**) | 0.021 | |||
| Negative | 12 (21.4) | 1 (5.3) | 11 (29.7) | |
| Positive | 44 (78.6) | 18 (94.7) | 26 (70.3) | |
(*) data missing for one patient; (**) data missing for 3 patients.