Table 4. Univariable and multivariable estimates for effect of child and adulthood BMI liability on circulating CRP.

			MR–total effect			MVMR–direct effect
	nSNPs		β	95% C.I.	P-value	β	95% C.I.	P-value
CRP
age_10	190		0.35	[0.27 0.42]	2.87E-20	-0.04	[-0.14 0.06]	0.488
adult	339		0.56	[0.50 0.62]	2.62E-74	0.56	[0.47 0.65]	3.90E-38

nSNPs; number of SNPs associated with the exposure, β; MR effect estimate, 95% CI; 95% Confidence Interval for MR estimate, P-value; P-value for MR estimate.