Table 1. Analysis of β-adrenergic receptor manipulation by scRNA-seq.

(A) Cell counts and calculated percentages for proliferating/differentiating cells (Prolif/Diff) and ASCs in the Adrb1 KO single-cell libraries. p-values were calculated by chi-squared analysis between CONTROL and COLD libraries for the two genotypes. ***p<1E-5. (B) Cell counts and calculated percentages for Prolif/Diff cells and ASCs in the CONTROL and CL-treated single-cell libraries. p-values were calculated by chi-squared analysis between CONTROL and CL libraries. ***p<1E-5.

A	Library	Number ofProlif/Diff Cells	Number ofASCs	Percent of Prolif/Diff Cells out of Total ASCs (%)
	CONTROL, WT	31	3,695	0.84
	COLD, WT	437	5,118	8.54***
	CONTROL, Adrb1 KO	9	1,543	0.58
	COLD, Adrb1 KO	171	3,063	5.58***
B	Library	Number ofProlif/Diff Cells	Number of ASCs	Percent of Prolif/Diff Cells out of Total ASCs (%)
	CONTROL	38	7,234	0.53
	CL	1,526	11,275	13.5***