Movie 6. Overview of the composite structure of the human NPC cytoplasmic face.

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The structures are shown docked into the cryo-ET reconstruction of the intact human NPC, colored according to Fig. 8. A pentameric bundle of NUP358^NTD is docked followed by relative placement of NUP358^OE and additional NUP358 domains, followed by the CFNC components. An overview of a single-spoke cytoplasmic face protomer is shown followed by a comparison cytoplasmic and nuclear face protomers.