Figure 5.

Absence of TUFM improved the apoptosis and reduced the proliferation of PASMCs. (a) TUFM, Bax, and Bcl2 expression under hypoxia condition. (b–d) Densitometry data represent the intensity of each group. (e) Cell viability tested by CCK-8 under hypoxia condition. (f) Quantification of proliferation level in smooth muscle cell by EdU assay kit. (g) Cell proliferation activity of each group under hypoxia. Scale bar: 50 μm. Data is presented as mean ± SD. ^∗P < 0.05, ^∗∗P < 0.01, and ^∗∗∗P < 0.001.