Table 6.
Sensitivity and specificity of components of 2016 MAS classification criteria.
| SJIA with MAS | SJIA without MAS | P value | Sensitivity (%) | Specificity (%) | Positive predictive value (%) | Negative predictive value (%) | |
|---|---|---|---|---|---|---|---|
| Ferritin > 684 μg/L | 8/8 | 10/18 | 0.023 | 100 (63.1-100) | 44.4 (21.5-69.2) | 44.4 (34.6-54.7) | 100 |
| PLT ≤ 181 × 109/L | 4/8 | 1/24 | 0.002 | 50 (15.7-84.3) | 95.8 (78.9-99.9) | 80 (34.2-96.9) | 85.2 (74.1-92.0) |
| Fibrinogen ≤ 10, 6 μmol/L | 5/7 | 2/11 | 0.024 | 71.4 (29-96.3) | 81.8 (48.2-97.7) | 71.4 (39.6-90.5) | 81.8 (57.5-93.8) |
| Triglycerides > 1.76 mmol/L | 6/7 | 3/12 | 0.011 | 85.7 (42.1-99.6) | 75 (42.8-94.5) | 66.7 (41.8-84.8) | 90 (58.8-98.3) |
| ALT > 48 U/L | 5/8 | 3/24 | 0.005 | 62.5 (24.5-91.5) | 87.5 (67.6-97.3) | 62.5 (33.7-84.5) | 87.5 (73.9-94.6) |
PLT: platelets; ALT: alanine aminotransferase. Sensitivity, specificity, positive predictive values, and negative predictive values are expressed as percentages with 95% confidence interval in parenthesis. P values are obtained using Pearson chi-square test.