Table 1.
Serum parameters related to liver function in normal rats and in rats injected with DXR (without and with the supplementation of rutin and/or quercetin).
| Parameter | |||||
|---|---|---|---|---|---|
| Groups | ALT (U/L) | AST (U/L) | ALP (U/L) | Bilirubin (mg/dL) | Albumin (g/dL) |
| Normal control | 57.50 ± 4.06 | 152.25 ± 5.68 | 180.50 ± 0.12 | 0.35 ± 6.40 | 3.12 ± 0.04 |
| DXR-injected control group | 101.00 ± 16.69++ | 261.33 ± 18.18++ | 276.50 ± 19.23++ | 0.53 ± 5.16++ | 2.48 ± 0.18++ |
| DXR-injected group supplemented with rutin | 65.50 ± 4.52∗∗ | 162.00 ± 1.80∗∗ | 131.00 ± 5.39∗∗$ | 0.40 ± 4.93∗∗ | 2.65 ± 0.14 |
| DXR-injected group supplemented with quercetin | 48.00 ± 4.28∗∗ | 183.00 ± 9.12∗∗ | 79.66 ± 2.44∗∗ | 0.56 ± 2.84$$ | 2.96 ± 0.09∗∗ |
| DXR-injected group supplemented with rutin and quercetin | 49.00 ± 4.75∗∗ | 176.83 ± 15.61∗∗ | 102.66 ± 7.18∗∗ | 0.43 ± 0.10∗ | 2.92 ± 0.02∗ |
| F-probability | P < 0.001 | P < 0.001 | P < 0.001 | P < 0.001 | P < 0.001 |
Values are M ± SE (n = 6). +P < 0.05, ++P < 0.01: the DXR-injected control group versus (vs.) normal control. ∗P < 0.05, ∗∗P < 0.01: the DXR-injected groups treated with rutin and/or quercetin vs. DXR-injected control group. $P < 0.05, $$P < 0.01: the DXR-injected groups treated with rutin or quercetin alone vs. DXR-injected group treated with rutin and quercetin mixture.