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Comparison of spectra of growth-dependent and adaptive non-IS-mediated mutationsa
| Category | Growth-dependent (early-arising) mutations | Adaptive (late-arising) mutations |
|---|---|---|
| A:T→G:C | 3 | 8 |
| G:C→A:T | 14 | 15 |
| G:C→T:A | 24 | 27 |
| G:C→C:G | 3 | 2 |
| A:T→C:G | 5 | 8 |
| A:T→T:A | 5 | 8 |
| −1 base frameshifts | 8 | 6 |
| +1 base frameshifts | 1 | 4 |
| Duplications | 2 | 2 |
| Deletions | 9 | 5 |
| Total | 74 | 85 |
In each of the two double mutants the two mutations were counted as independent events in this table.
