FIGURE 1.

Comparison of anti‐spike IgG response between healthy controls, FL and WM treatment cohorts at T3. In FL (A), there is no difference in response comparing HC with TN, but there is a significantly reduced response in the ICT cohort compared to HC and TN. In WM (B), there is no difference in response comparing HC with TN or ICT, but there is a significantly reduced response BTKi with both HC and TN. A p < .03 was considered statistically significant in A and <.01 in B after Bonferroni correction. BTKi, BTKi‐treated cohort; HC, healthy controls; ICT, immunochemotherapy‐treated cohort; IgG, immunoglobulin G; MFI, delta mean fluorescence intensity; TN, treatment naïve cohort. **p < .01; ***p < .001; ****p < .0001