TABLE 1.
Baseline characteristics and past medical history of the participants
| Characteristics | SpikoGen® | Placebo |
|---|---|---|
| N = 250 | N = 50 | |
| Sex—n (%) | ||
| Male | 114 (45.60) | 18 (36) |
| Age (years)—mean ± SD | 44.04 ± 16.05 | 48.99 ± 18.10 |
| First vaccination platform—n (%) | ||
| Inactivated whole virus | 142 (56.8) | 28 (56.0) |
| Viral vector | 56 (22.4) | 12 (24.0) |
| SpikoGen® | 52 (20.8) | 10 (20.0) |
| Seropositive at baseline—n (%) | ||
| Inactivated whole virus | 54 (38.03) | 11 (39.29) |
| Viral vector | 29 (51.79) | 5 (41.67) |
| SpikoGen® | 28 (53.85) | 5 (50) |
| Medical history—frequency (%) a | ||
| Anxiety/depression | 4 (1.6) | 3 (6) |
| Arrhythmia | 5 (2) | 0 (0) |
| Asthma | 2 (0.8) | 0 (0) |
| Cerebrovascular accident | 18 (7.2) | 7 (14) |
| Deep vein thrombosis | 13 (5.2) | 4 (8) |
| Diabetes mellitus | 15 (6) | 2 (4) |
| Dyslipidemia | 18 (7.2) | 6 (12) |
| Hepatic steatosis | 18 (7.2) | 4 (8) |
| Hypothyroidism | 2 (0.8) | 0 (0) |
| Malignancy | 9 (3.6) | 2 (4) |
| Multiple sclerosis | 5 (2) | 2 (4) |
| Ischemic heart disease | 6 (2.4) | 1 (2) |
| Nephrolithiasis | 12 (4.8) | 2 (4) |
| Osteoarthritis | 5 (2) | 1 (2) |
| Rheumatoid arthritis | 2 (0.8) | 1 (2) |
| Other autoimmune disorders | 17 (6.8) | 7 (14) |
a
Malignancy includes Prostate cancer and breast cancer. Other autoimmune disorders include Ankylosing spondylitis, Autoimmune thyroiditis, Behcet's syndrome, Cutaneous vasculitis, Hyperthyroidism, Inflammatory bowel disease, Lichen planus, Psoriasis and Psoriatic arthropathy.