TABLE 3.
Pooled | SpikoGen® | Inactivated virus | Viral vector | |||||
---|---|---|---|---|---|---|---|---|
SpikoGen® | Placebo | SpikoGen® | Placebo | SpikoGen® | Placebo | SpikoGen® | Placebo | |
sVNTw | ||||||||
Day 14 (n) | 199 | 39 | 41 | 9 | 109 | 21 | 49 | 9 |
GMFR | 18.83 | 1.34 | 11.33 | 1.46 | 25.77 | 1.40 | 14.32 | 1.13 |
95% CI | (14.71–24.10) | (1.15–1.56) | (6.45–19.92) | (1.04–2.04) | (18.51–35.87) | (1.09–1.79) | (8.81–23.27) | (0.97–1.31) |
S1w‐IgG | ||||||||
Day 14 (n) | 199 | 39 | 41 | 9 | 109 | 21 | 49 | 9 |
GMFR | 5.92 | 1.09 | 5.11 | 1.18 | 7.49 | 1.11 | 3.97 | 0.98 |
95% CI | (4.94–7.10) | (0.99–1.21) | (3.10–8.44) | (0.89–1.56) | (5.93–9.45) | (0.98–1.25) | (2.91–5.42) | (0.74–1.30) |
RBDw‐IgG | ||||||||
Day 14 (n) | 199 | 39 | 41 | 9 | 109 | 21 | 49 | 9 |
GMFR | 11.24 | 1 | 7.59 | 1.11 | 17.06 | 1.05 | 6.81 | 0.81 |
95% CI | (8.77–14.42) | (0.87–1.15) | (4.29–13.41) | (0.87–1.43) | (12.25–23.77) | (0.93–1.18) | (3.89–9.83) | (0.47–1.40) |
Note: The 95% confidence interval (CI) for geometric mean fold rise (GMFR) was calculated based on the t‐distribution of the log‐transformed values, then back‐transformed to the original scale for presentation.