FIGURE 2.

Effect of spike protein on collagen‐induced hPRP aggregation from vaccinated and non‐vaccinated individuals. Platelet aggregation with collagen was defined as the difference between the 0% (PRP) baseline and the 100% (PPP) baseline: (A). hPRP from vaccinated individuals. (1A) Collagen 0.8 μg/ml. (1B) 1 min pre‐incubation with 20 μg/ml spike protein and addition of collagen 0.8 μg/ml. (1C) Collagen 0.8 μg/ml, 2 μg/ml spike protein added 10 s after collagen (see arrow). (B). hPRP from non‐vaccinated individuals. (2A) Collagen 0.8 μg/ml. (2B) 1 min pre‐incubation with 2 μg/ml spike protein and addition of collagen 0.8 μg/ml. (2C) 1 min pre‐incubation with 20 μg/ml spike protein and addition of collagen 0.8 μg/ml. (2D) 10 min pre‐incubation with 20 μg/ml spike protein and addition of collagen 0.8 μg/ml