TABLE 2.

Hydrogen bonding in docked pose of Chloroquine and Hydroxychloroquine [128, 129]

Compound	Type of bond	Donor	Acceptor	Bond distance (Å)
Chloroquine	Hydrogen bond	ASN 501 (H)	CQ (N)	2.61
Chloroquine	Π‐donor Hydrogen bond	GLY 496 (H)	CQ (π‐orbitals)	2.86
Hydroxychloroquine	Hydrogen bond	TYR 449 (H)	HCQ (N)	1.93
Hydroxychloroquine	Hydrogen bond	GLY 502 (H)	HCQ (O)	1.81
Hydroxychloroquine	Hydrogen bond	HCQ 29 (H)	GLY 496 (O)	2.30
Hydroxychloroquine	Hydrogen bond	HCQ 29 (H)	GLN 498 (O)	3.09
Hydroxychloroquine	Π‐donor Hydrogen bond	TYR 449 (H)	HCQ (O)	2.77