TABLE 1.
Demographics, laboratory and histopathological characteristics of patients with autoimmune hepatitis following COVID‐19 vaccination at University Malaya Medical Centre (UMMC)
Patient | Age (years) | Gender | Latency (Days) | ALP/AST at presentation (U/L) | ALP/ALT at presentation (U/L) | Bilirubin at presentation (μmol/L) | Antibodies | IgG (mg/dL) | Liver biopsy results |
---|---|---|---|---|---|---|---|---|---|
1 | 59 | Female | 12 | 189/962 | 189/1178 | 126 | – | 1740 | Lympho‐plasma‐cellular portal infiltrates with no biliary features |
2 | 63 | Female | 14 | 299/505 | 299/354 | 313 | ANA | 2030 |
Bridging fibrosis consistent with underlying PSC. Presence of interface and lobular hepatitis |
3 | 72 | Female | 10 | 125/1452 | 125/2280 | 29 | AMA | 1940 | Portal inflammatory cell infiltration comprises mostly of lymphocytes and plasma cells with foci of lobular inflammation and hepatocyte necrosis |