TABLE 1.
Demographic and laboratory parameters of acute and convalescent COVID‐19 cohorts
| Parameters | Normal range | Convalescent COVID‐19 (n = 50) | Acute COVID‐19 (n = 36) |
|---|---|---|---|
| Demographic data | |||
| Age, median (IQR) | 50 (27) | 62 (16) | |
| Male – n (%) | 30 (60) | 27 (75) | |
| BMI, median (IQR) | 28 (7) | 30 (9) | |
| Comorbidity count, median (IQR) | 1 (3) | 3 (2) | |
| Hospitalization – n (%) | 37 (74) | 36 (100) | |
| ICU – n (%) | 8 (16) | 18 (50) | |
| Laboratory parameters at time of blood sampling – median (IQR) | |||
| Leukocytes (×109/L) | 4–11 | 6.3 (1.7) | 7.8 (5.3) |
| Lymphocytes (×109/L) | 1.5–3.5 | 1.9 (0.7) | 1.1 (0.7) |
| Neutrophils (×109/L) | 2–7.5 | 3.3 (1.2) | 5.9 (5.4) |
| Platelets (×109/L) | 140–450 | 272 (60) | 276 (145) |
| Creatinine (μmol/L) | 45–84 | 73 (26) | 72 (34) |
| Fibrinogen (g/L) | 1.9–3.5 | 2.9 (0.8) | 4.8 (2.8) |
| D‐dimer (ng/ml) | 0–500 | 377 (251) | 980 (1619) |
| CRP (mg/ml) | 0–5 | 1.1 (1) | 110 (173) |
| IL‐6 (pg/ml) | 0–7.26 | 1.5 (3.6) | 76.6 (144.4) |
| Clinical parameters Convalescent COVID‐19 only – median (IQR) unless otherwise stated | |||
| Time to follow‐up (days) | 68 (11) | NA | |
| 6MWT distance (m) | 400–700 | 430 (160) | NA |
| Lowest desaturation (%) | 95 (2) | NA | |
| Abnormal chest X‐ray – n (%) | 3 (6) | NA | |
Abbreviations: 6MWT, 6‐minute walking test; BMI, body mass index; COVID‐19, coronavirus disease 2019; CRP, C‐reactive protein; ICU, intensive care unit; IL, interleukin; IQR, interquartile range.