Table 2.
Demographics and clinical outcomes based on survival in CT COVID cohort (n = 95)
| Alive (n = 79) | Dead (n = 16) | P‐value 1 | |
|---|---|---|---|
| Clinical outcomes | |||
| Age (in years) (mean (SD)) | 63.1 (13.7) | 64.3 (17.4) | 0.773 |
| Sex (female) (%) | 37 (46.8) | 8 (50.0) | 1 |
| BMI 2 (mean (SD)) (kg/m2) | 32.5 (9.26) | 29.2 (6.39) | 0.177 |
| Race (African‐American) (%) | 21 (26.6) | 4 (25.0) | 1 |
| Hospital length of stay (in days) (median (IQR)) | 13.0 (6.0, 28.0) | 21.0 (13.8, 37.3) | 0.028* |
| ICU admission (%) | 39 (49.4) | 13 (81.2) | 0.039 |
| Mechanical ventilation (%) | 25 (69.4) | 13 (92.9) | 0.17 |
| PM CSA (initial) (cm2) (median (IQR)) | 33.1 (26.0, 47.0) | 31.0 (27.2, 34.9) | 0.383* |
| PM CSA (final) (cm2) (median (IQR)) | 32.1 (24.1, 42.2) | 27.6 (24.8, 29.1) | 0.076* |
| Per cent change in PM CSA (cm2) (standardized to 30 days) (median (IQR)) | −1.14 (−5.17,‐0.24) | −2.69 (−8.81,‐1.54) | 0.037 |
| ESM CSA (initial) (cm2) (median (IQR)) | 37.0 (30.8, 46.8) | 27.8 (24.5, 37.3) | 0.025* |
| ESM CSA (final) (cm2) (median (IQR)) | 35.1 (27.2, 43.3) | 27.10 (23.7, 31.4) | 0.009* |
| Per cent change in ESM CSA (cm2) (standardized to 30 days) (mean (SD)) | −0.81 (−4.62,‐0.10) | −2.18 (−10.9,‐0.70) | 0.089 |
| Lab results (on admission) (mean (SD)) | |||
| CRP 2 (mg/L) | 4.60 (1.75, 12.1) | 14.5 (2.80, 22.4) | 0.052* |
| Procalcitonin (ng/mL) | 0.17 (0.09, 0.33) | 0.24 (0.13, 0.82) | 0.154* |
| Lactate (mmol/L) | 1.63 (0.77) | 2.14 (3.01) | 0.359 |
| d‐dimer (ng/mL) | 1050 (600, 2760) | 3175 (1065, 5440) | 0.044* |
| WBC 2 (103 cells/μL) | 6.80 (5.12, 8.61) | 7.19 (5.02, 10.2) | 0.865* |
| Absolute lymphocyte count (cells/μL) | 1.03 (1.18) | 1.14 (1.16) | 0.740 |
1
P‐values represent pairwise Student's two‐tailed t‐tests for normally distributed continuous variables and Wilcoxon–Mann–Whitney rank sum test for non‐normally distributed variables (denoted by *). Non‐normally distributed variables are presented as median with interquartile range. Difference from control, P < 0.05.
2
BMI = body mass index; WBC = white blood cells; CRP = C‐reactive protein.