Table 2.
Comparison of patients with post-operative hypoparathyroidism and those without
| Group 1 Hypoparathyroidism (+) | Group 2 Hypoparathyroidism (-) | p | |
|---|---|---|---|
| Age | 48±13.7 | 48.3±12.8 | 0.774 |
| Gender | 0.956 | ||
| Female n (%) | 127 (77%) | 291 (77.2%) | |
| Male n (%) | 38 (23%) | 86 (22.8%) | |
| Pre-operative Hyperthyroidism (%) | 40 (%24.2) | 107 (%28.4) | 0.319 |
| Pre-operative Parathyroid Hormone mean±SD (ng/L) Min-max | 56.7±29.1 (23–197) | 56.5±27 (19–193) | 0.517 |
| Pre-operative Calcium mean±SD (mg/dl) Min-max | 9.5±0.4 (7.6–10.69) | 9.5±0.4 (8–10.69) | 0.573 |
| Pre-operative Phosphorus mean±SD (mg/dl) Min-max | 3.4±0.6 (1.8–5.3) | 3.3±0.6 (1.4–5.3) | 0.136 |
| Pre-operative Magnesium mean±SD (mg/dl) Min-max | 1.9±0.2 (1.2–2.4) | 1.9±0.2 (1.2–2.7) | 0.641 |
| Pre-operative ALP mean±SD (U/L) Min-max | 76±26 (35–173) | 82±34 (15–232) | 0.198 |
| Pre-operative Cr mean±SD (mg/dl) Min-max | 0.69±0.15 (0.35–1.1) | 0.73±0.19 (0.33–1.82) | 0.121 |
| Pre-operative 25(OH)vitD3 ort±SD (ng/ml) Min-max | 19. .7±13.6 (3–89.7) | 16.7±12.3 (2–94.3) | 0.019 |
| Categorical Pre-operative 25(OH)vitD3 (n:321) | 0.118 | ||
| <8.6 | 21 (19.8%) | 59 (27.4%) | |
| 8.7–14.9 | 22 (20.8%) | 59 (27.4%) | |
| 15–23.7 | 31 (29.2%) | 49 (22.8%) | |
| >23.8 | 32 (30.2%) | 48 (22.3%) | |
| Total (n) | 106 | 215 | |
| The number of parathyroid glands identified during surgery n (%) | 0.462 | ||
| 0 | 2 (1.2%) | 8 (2.1%) | |
| 1 | 6 (3.6%) | 15 (4%) | |
| 2 | 16 (9.7%) | 56 (14.9%) | |
| 3 | 40 (24.2%) | 88 (23,3%) | |
| 4 | 101 (61.2%) | 210 (55.7%) | |
| Total | 165 | 377 | |
| PT AT n (%) | 26 (15.8 %) | 30 (8%) | 0.006 |
| PT on Pathological Specimen n (%) | 33 (20%) | 40 (10.6%) | 0.003 |
| PGRIS n (%) | 0.000 | ||
| 0 | 0 | 1 (0.3%) | |
| 1 | 3 (1.8%) | 0 | |
| 2 | 10 (6.1%) | 5 (1.3%) | |
| 3 | 40 (24.2%) | 54 (14.3%) | |
| 4 | 112 (67.9%) | 317 (84.1%) | |
| Total | 165 | 377 | |
| Central Neck Dissection n (%) | 27 (16.4%) | 20 (5.3%) | 0.000 |
| Post-operative 1. day hypocalcemia | 64 (39.3%) | 56 (14.9%) | 0.000 |
| Post-operative 1. day Calcium mean+SD (mg/dl) Min-max | 8.2+0.7 (6.2–9.7) | 8.5+0.6 (6.5–10.5) | 0.000 |
SD: Standard deviation; min: minimum; max: maximum; PT: parathyroid; AT: Autotransplantation; PGRIS: The number of parathyroid glands remaining in situ; ALP: Alcaline phosphatase; Cr: Creatinine.