TABLE 3.

Risk of worsening of frailty condition according to frailty status at baseline and COVID‐19 positivity

Independent variable	Worsening of frailty status (ΔMPI ≥0.1)*
	Adjusted OR	95% CI	p‐value
Robust without COVID‐19 positivity	REF
Pre‐frail/frail without COVID‐19 positivity	14.84	4.26–51.74	<0.001
Robust with COVID‐19 positivity	2.53	0.23–27.99	0.449
Pre‐frail/frail with COVID‐19 positivity	12.77	2.66–61.40	0.001

Note. ^*Model adjusted for age, gender, BMI, multimorbidity (3 or more chronic diseases), flu vaccination and anti‐pneumococcal vaccination.

Abbreviations: ΔMPI, difference of MPI scores between 12 months follow‐up and baseline; CI, confidence interval; OR, odd ratio; MPI, Multidimensional Prognostic Index.