SUPPLEMENT MATERIAL 2.

Table 1 Normative data values for Pressure recovery time PRT 100 and PRT 50 in Valsalva Maneuver

PRT100
Male	Mean (SD)	95% Normative values (2.5th percentile to 97.5th percentile)		Female	Mean (SD)	95% Normative values (2.5th percentile to 97.5th percentile)
20-30	2.53 (0.82)	1.44	4.65	20-30	2.11 (0.51)	1.28	3.04
31-40	2.57 (0.90)	1.62	4.69	31-40	2.48 (0.94)	1.50	4.56
41-50	2.36 (0.63)	1.59	3.62	41-50	2.47 (0.63)	1.44	5.28
51-60	2.84 (0.74)	1.77	4.18	51-60	2.79 (1.08)	1.38	5.00
61-70	3.71 (1.56)	2.01	6.86	61-70	2.98 (1.09)	1.49	4.64
≥71	5.99 (3.41)	1.29	10.67	≥71	3.16 (1.95)	1.43	7.05
PRT50
Male	Mean (SD)	95% Normative values (2.5th percentile to 97.5th percentile)		Female	Mean (SD)	95% Normative values (2.5th percentile to 97.5th percentile)
20-30	1.16 (0.38)	0.59	1.95	20-30	0.97 (0.22)	0.70	1.50
31-40	1.22 (0.40)	0.72	2.25	31-40	1.18 (0.44)	0.64	2.03
41-50	1.11 (0.35)	0.69	1.79	41-50	1.21 (0.61)	0.74	2.58
51-60	1.33 (0.33)	0.89	1.93	51-60	1.25 (0.46)	0.70	2.23
61-70	1.81 (0.91)	0.89	3.90	61-70	1.35 (0.47)	0.68	2.07
≥71	2.71 (1.55)	0.54	4.88	≥71	1.52 (1.05)	0.75	3.71