Table. Classifier-Specific Patient Label Assignments and Assignment Probabilities Across the Case-Control Samples of the Study.
Case-label assignment | No. (%) | |||||||
---|---|---|---|---|---|---|---|---|
bvFTD (n = 108) | Established AD (n = 44) | MCI or early-stage AD (n = 96) | Schizophrenia (n = 157) | Major depression (n = 102) | HC (FTLDc) (n = 40) | HC (OASIS-3) (n = 138) | HC (Munich) (n = 335) | |
bvFTD vs HC classifier | 87 (80.6)a | 32 (72.7) | 54 (56.3) | 65 (41.4) | 22 (21.6) | 4 (10.0)a | 21 (15.2) | 30 (9.0) |
Schizophrenia vs HC classifier | 92 (85.5) | 31 (70.5) | 63 (65.6) | 105 (66.9)a | 55 (53.9) | 11 (27.5) | 42 (30.4) | 85 (25.4)a |
MCI or early-stage AD vs HC classifier | 80 (74.5) | 37 (84.1) | 67 (69.8)a | 47 (29.9) | 12 (11.8) | 4 (10.0) | 29 (21.0)a | 14 (4.2) |
Established AD vs HC classifier | 80 (74.5) | 35 (79.5)a | 62 (64.6) | 28 (17.8) | 3 (2.9) | 3 (7.5)a | 13 (9.4) | 6 (1.8) |
Abbreviations: AD, Alzheimer disease; bvFTD, behavioral-variant frontotemporal dementia; FTLDc, the German Frontotemporal Lobar Degeneration Consortium; HC, healthy control; MCI, mild cognitive impairment.
Derivation samples of the respective diagnostic classifier.