Change from baseline to 6 months in patient-reported and clinical outcomes with Bonferroni-adjusted 95% CIs, demonstrated as % change from baseline mean. BDI, Beck’s Depression Inventory; BMI, body mass index; EDSS, Expanded Disability Status Scale; MFIS, Modified Fatigue Impact Scale; MSFSS, Multiple Sclerosis Fatigue Severity Scale; MSQoL, Multiple Sclerosis Quality of Life; PASAT, Paced Auditory Serial Addition Test; SDMT, Symbol Digit Modality Test.