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. 2022 Jul 22;48(3):164. doi: 10.3892/or.2022.8379

Figure 2.

Figure 2.

miR-491-3p overexpression inhibits viability, proliferation, migration and invasion, and promotes apoptosis in NSCLC cells. (A) Cell Counting Kit-8 assay illustrated that miR-491-3p overexpression inhibited NSCLC cell viability. (B) Edu experiment indicated that miR-491-3p overexpression inhibited NSCLC cell proliferation. 200× magnification. Scale bar: 50 µm. (C) Matrigel experiment indicated that miR-491-3p overexpression suppressed NSCLC cell invasion. 200× magnification. Scale bar: 50 µm. (D) Wound healing assay revealed that miR-491-3p overexpression suppressed NSCLC cell migration. (E) Flow cytometry was used to measure cell apoptosis. miR-491-3p overexpression promoted NSCLC cell apoptosis. *P<0.05 and **P<0.01. miR, microRNA; NSCLC, non-small cell lung cancer; NC, negative control.