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. 2022 Jul 22;48(3):164. doi: 10.3892/or.2022.8379

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — miR-491-3p overexpression suppresses the in vivo growth of NSCLC. (A and B) The volume and weight of xenograft tumor tissues was measured. (C) Reverse transcription-quantitative PCR was implemented to detect the expression of miR-491-3p and FGF5 mRNA in xenograft tumor tissues. (D) Immunohistochemical analysis was carried out to detect the expression of Ki67 and FGF5 protein in xenograft tumor tissues. 200× magnification. Scale bar: 100 µm. **P<0.01. miR, microRNA; NSCLC, non-small cell lung cancer; FGF5, fibroblast growth factor 5; NC, negative control.