Table II.
Cx32 expression in HCC | |||||
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Clinical characteristics | Variables | No. of patients | Positive expression | Negative expression | P-value |
Age (years) | ≤56 | 44 | 22 | 21 | 0.061 |
>56 | 41 | 12 | 29 | ||
Sex | Female | 22 | 7 | 15 | 0.306 |
Male | 63 | 27 | 35 | ||
Alpha-fetoprotein (ng/ml) | ≤400 | 25 | 10 | 15 | 0.0485 |
>400 | 60 | 24 | 35 | ||
HBV infection | Yes | 51 | 22 | 34 | 0.462 |
No | 28 | 12 | 16 | ||
Liver cirrhosis | Yes | 66 | 28 | 37 | 0.325 |
No | 19 | 6 | 13 | ||
Histological differentiation | Poorly | 13 | 6 | 7 | 0.559 |
Moderately | 64 | 24 | 39 | ||
Well | 8 | 4 | 4 | ||
Tumor capsule | Yes | 16 | 3 | 13 | 0.071 |
No | 69 | 31 | 37 | ||
Tumor size (cm) | ≤5 | 46 | 21 | 25 | 0.288 |
>5 | 39 | 13 | 25 | ||
Vital status | Deceased | 34 | 16 | 17 | 0.236 |
Living | 51 | 18 | 33 | ||
Follow-up time (months) | ≤60 | 34 | 16 | 17 | 0.229 |
>60 | 51 | 18 | 33 |
HCC, hepatocellular carcinoma; Cx32, connexin 32; HBV, hepatitis B virus.