Table 1.
Colorectal Cancer Screening Guidelines for Individuals with a Family History of Advanced Colorectal Polyp
| Family history | Age to initiate screening | Preferred test, interval | |
|---|---|---|---|
|
|
|||
| Banff Consensus Group (CAG/AGA) 20 | Documented advanced adenoma in ≥ 1 FDR (any age) | Age 40–50, or 10y younger than age at diagnosis of FDR* | Colonoscopy every 5–10y or FIT every 1–2 y |
|
| |||
| United States Multi Society Task Force (US-MSTF) 19 | Documented Advanced adenoma in 1 FDR <60y or in 2 FDRs (any age) | Age 40, or 10y younger than age of diagnosis of FDR* | Colonoscopy every 5y# |
|
| |||
| Advanced adenoma in 1 FDR ≥60y | Age 40 | Same as average-risk persons (colonoscopy every 10y or FIT annually) | |
|
| |||
| Documented Advanced serrated lesion in ≥1 FDR^ | According to recommendations for family history of documented advanced adenoma | ||
|
| |||
| National Comprehensive Cancer Network (NCCN) 65 | Confirmed Advanced adenoma or advanced serrated lesion in 1 FDR (any age) | Age 40, or at age of diagnosis of advanced adenoma in FDR* | Colonoscopy every 5–10y |
y: years, CAG: Canadian Association of Gastroenterology, AGA: American Gastroenterological Association, US-MSTF: United States Multi Society Task Force, NCCN: National Comprehensive Cancer Network, FDR: first degree relative, ASL: advanced serrated lesion, FIT: fecal immunochemical test
whichever is earlier
If colonoscopy is declined, annual FIT should be offered
Advanced Serrated Lesion- weak recommendation, very low quality evidence
American Cancer Society (ACS) 2018 Guidelines:103 Only for average-risk adults, no screening guidelines specifically for people at increased or high risk of colorectal cancer, recommend referring to US MSTF guidelines.