Table 3.
Mislocalization of cytokinesis regulators in CRS-depleted HeLa cells
| CR | Mock | BAF53a | Tip60 |
|---|---|---|---|
| CIT-K | 2.03 ± 0.47 | 11.44 ± 2.28*** | 18.99 ± 3.48*** |
| MKLP2 | 1.94 ± 1.71 | 1.55 ± 0.49 | 32.21 ± 2.28*** |
| Aurora B | 3.20 ± 3.02 | 8.47 ± 0.18*** | 8.25 ± 3.18*** |
| MKLP1 | 0.73 ± 0.64 | 8.66 ± 2.57*** | 55.16 ±3.42*** |
| Cep55 | 2.77 ± 0.20 | 32.00 ± 2.94*** | 42.56 ± 3.59*** |
| Anillin | 2.72 ± 0.98 | 71.58 ± 4.36*** | 66.44 ± 2.98*** |
| Alix | 3.27 ± 2.03 | 37.75 ± 2.05*** | 53.39 ± 4.29*** |
| Spastin | 4.27 ± 2.18 | 46.27 ±5.79*** | 46.51 ± 5.80*** |
The results are expressed as mean ± SD values from three independent replicate experiments
CR cytokinesis regulators
Experimental groups were compared with control groups (mocks) by Fisher's exact test. *=P < 0.05; **=P < 0.005; and ***P= < 0.0005