Table 1.
Histopathology scores and severity of acute pancreatitis in all groups
| Groups | n | Pancreas pathology | Severity | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Neutrophil infiltration | Edema | Necrosis | None | Mild | Moderate | Severe | |||||||||||
| 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | ||||||
| Con | 6 | 6 | - | - | 6 | - | - | - | 6 | - | - | - | 6 | - | - | - | |
| AP | 6 | - | 3 | 1 | 2 | - | 2 | 3 | 1 | - | 2 | 3 | 1 | - | - | 4 | 2 |
| LG | 6 | 1 | 4 | 1 | - | - | 4 | 2 | - | 1 | 3 | 2 | - | - | 4 | 2 | - |
| HG | 6 | 5 | - | 1 | - | - | 6 | - | - | 3 | 2 | - | 1 | - | 5 | 1 | - |
Each section was scored according to the criteria described by H. E. V. DE COCK et al. in 2007 [15]. The histological grading ranges from 0–3 (0 = Not present; 1 = Mild or < 25% of the pancreatic parenchyma; 2 = Moderate or present in 25–50% of the parenchyma; 3 = Severe or > 50% of the parenchyma)
The severity of AP was classified according to the total score as follows: 0 = none 1–3 = mild 4–6 = moderate 7–9 = severe
Abbreviations: Con Control group, AP Acute pancreatitis group, LG Low-dose genistein group, HG High-dose genistein group