Table 2.

Effect of genistein on MPO, NF-kB, 4-HNE expression and acinar cell apoptosis in acute pancreatitis mice

Groups (n = 6)	Parameters
	MPO positive (cells of HPF)	NF-kB Positive cells (%)	4-HNE Positive cells (%)	TUNEL Positive cells (%)
Con	0.33 ± 0.08	0.44 ± 0.01	0.40 ± 0.02	0.07 ± 0.01
AP	21.00 ± 4.60a1	0.75 ± 0.01a1	0.76 ± 0.01a1	0.22 ± 0.01a1
LG	4.13 ± 0.73b1	0.47 ± 0.01a2,b1	0.45 ± 0.01a2,b1	0.09 ± 0.00a2,b1
HG	2.97 ± 0.44b1	0.46 ± 0.01b1	0.43 ± 0.01b1	0.07 ± 0.00b1

Data are express as mean ± SEM. ^a1p < 0.01, ^a2p < 0.05 vs. Con group; ^b1p < 0.01, ^b2p < 0.05 vs. AP group

Abbreviations: Con Control group, AP Acute pancreatitis group, LG Low dose of genistein group, HG High dose of genistein group, MPO Myeloperoxidase, NF-kB Nuclear factor-kappa beta, 4-HNE 4-Hydroxynonenal, TUNEL Terminal deoxynucleotidyl transferase dUTP nick end labeling