Skip to main content
. 2022 Aug 3;19:198. doi: 10.1186/s12974-022-02558-z

Fig. 8.

Fig. 8

Activation of NK1R or PKCδ abolished the effects of Aprepitant after ICH. AC Modified Garcia test, forelimb placement test, and corner turn test at 24 h after ICH. D Representative western blot bands, E quantitative analyses of p-PKCδ, NLRC4, N-GSDMD, C-Caspase-1, IL-18, and IL-1β at 24 h after ICH. Data were represented as mean ± SD. * p < 0.05 vs Sham, @ p < 0.05 vs ICH + vehicle, % p < 0.05 vs ICH + Aprepitant + DMSO; & p < 0.05 vs ICH + Aprepitant + DMSO; one-way ANOVA, Tukey post hoc test, n = 6/group